PLEKHO2 — Pleckstrin homology domain containing O2
PLEKHO2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLEKHO2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Angiogenesis Endothelial cell development | FAM241A, FAM43A, KLF6, MYC, NFATC1, PHLDA1, PIM3, RALGDS +7 more | View in SCUBA |
| Gamma-delta T cells | XCL1/XCL2 Cytotoxic Activation cytotoxicity | BCL2A1, CCL3L3, CCL4L2, FASLG, ICAM1, IRF8, RILPL2, SNX18 +6 more | |
| Macrophages | Macrophage Endocytic Signaling Lysosomal & pahgocytosis | APLP2, ARHGAP30, ARHGEF2, ATF6B, BAG6, CLSTN1, CMTR2, CTBS +20 more | View in SCUBA |
About the gene
| Synonyms | DKFZp761K2312, PLEKHQ1, PP1628, pp9099 |
|---|---|
| Chromosome | 15: 64841883-64868002 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.