RAP1GAP2 — RAP1 GTPase activating protein 2
RAP1GAP2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RAP1GAP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Secretory progenitor Notch Epithelial development | ADAMTS14, ADCY5, ADGRG4, DOCK8, HEPACAM2, MEIS1, NBPF14, NBPF19 +5 more | View in SCUBA |
| Gamma-delta T cells | TGF-β Migration Program migration & adhesion | AGTPBP1, AHNAK, CAPN2, CYTH1, FLNA, RASA3, SORL1, SYNE1 +2 more | |
| Mucosal-associated invariant T cell | Cytoskeletal Migration migration & adhesion | ADGRG5, AGAP1, BCL2, CDK6, JAKMIP2, NSF, PARP15, PIK3R5 +9 more | |
| Neutrophils | Stress Kinase Signaling Stress | ANKRD44, APBB1IP, HIPK3, IGF1R, MAP3K5, MEF2A, NEK7, PARP8 +2 more |
About the gene
| Synonyms | GARNL4, KIAA1039 |
|---|---|
| Chromosome | 17: 2755705-3037741 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP- bound state
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.