PARP15 — Poly(ADP-ribose) polymerase family member 15
PARP15 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PARP15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Interferon Response Anti-viral | ACAP1, ARHGAP15, BCL2, CD44, CD46, DSE, EML4, FCGR2B +7 more | View in SCUBA |
| Gamma-delta T cells | TGF-beta Signaling Immune regulation | ABCF1, ABHD12, ACAP2, ADIPOR2, CBX6, ENPP4, FBXO9, GSAP +18 more | |
| Mucosal-associated invariant T cell | Cytoskeletal Migration migration & adhesion | ADGRG5, AGAP1, BCL2, CDK6, JAKMIP2, NSF, PIK3R5, PTPN4 +9 more |
About the gene
| Synonyms | ARTD7, BAL3, FLJ40597, pART7 |
|---|---|
| Chromosome | 3: 122577628-122639047 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Glycosyltransferase, Nucleotidyltransferase, Transferase |
| Biological process | Transcription, Transcription regulation |
Function
Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins. Acts as a negative regulator of transcription.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.