SAMD4A — Sterile alpha motif domain containing 4A
SAMD4A belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SAMD4A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Procoagulant TGF-β Response Inflammation | CITED4, CSF3, EHD1, F3, LAMC1, LIPG, MED24, PLEKHO1 +7 more | View in SCUBA |
| Lymphatic endothelial | NF-κB Innate Signaling Inflammation | AKAP13, B4GALT5, BACH1, CHD2, CNST, DENND5A, HIVEP1, HIVEP2 +11 more | View in SCUBA |
About the gene
| Synonyms | DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA |
|---|---|
| Chromosome | 14: 54566117-54793315 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Translation regulation |
Function
Acts as a translational repressor of SRE-containing messengers
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.