CSF3 — Colony stimulating factor 3
CSF3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CSF3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Procoagulant TGF-β Response Inflammation | CITED4, EHD1, F3, LAMC1, LIPG, MED24, PLEKHO1, PMEPA1 +7 more | View in SCUBA |
| Fibroblasts | Cytokine Chemokine Secretion Inflammatory | CCL2, CXCL1, CXCL3, CXCL8, G0S2, GLIS3, IL6, RIPK2 +1 more | View in SCUBA |
| Lymphatic endothelial | Genotoxic Innate Inflammation Inflammation | CSF2, E2F7, GBP2, NBN, PLA1A, RIPK2, SELENOM, SQOR +1 more | View in SCUBA |
About the gene
| Synonyms | C17orf33, G-CSF, GCSF, MGC45931 |
|---|---|
| Chromosome | 17: 40015361-40017813 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted secreted proteins |
| Molecular function | Cytokine, Growth factor |
Function
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.