LAMC1 — Laminin subunit gamma 1
LAMC1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LAMC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Procoagulant TGF-β Response Inflammation | CITED4, CSF3, EHD1, F3, LIPG, MED24, PLEKHO1, PMEPA1 +7 more | View in SCUBA |
| Fibroblasts | Basement Membrane ECM ECM production | BSG, COL6A1, COL6A2, COMT, ECE1, ECM1, FNDC3B, LAMB1 +2 more | View in SCUBA |
| Lymphatic endothelial | ECM-driven Migration migration & adhesion | FMNL2, GLIS3, MAML2, PCSK6, RAPH1, SGIP1, ST3GAL6, STK32B +2 more | View in SCUBA |
| Pericytes | Basement Membrane Assembly ECM production | F2R, FARP1, ITGB1, JAK1, LAMA4, LIMS1, NID1, PELO +1 more | View in SCUBA |
| Smooth muscle cells | Adhesion Activation Migration & adhesion | ANXA2, ATP1B3, CAPNS1, CD44, CYBRD1, FHL2, LGALS3, LGALS3BP +3 more | View in SCUBA |
About the gene
| Synonyms | LAMB2 |
|---|---|
| Chromosome | 1: 183023420-183145592 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Biological process | Cell adhesion |
Function
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.