SLC12A2 — Solute carrier family 12 member 2
SLC12A2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SLC12A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Ion Transport Homeostasis Housekeeping | APP, ATP1A1, CAPRIN1, CSDE1, EEF2, MAT2B, TMEM123, VPS35 | View in SCUBA |
| Pericytes | Pericyte Vascular Identity Developmental | AHR, ARHGAP29, CA4, CD46, MEF2C, MYO6, NOTCH1, PDE1C +10 more | View in SCUBA |
About the gene
| Synonyms | BSC-2, BSC2, CCC1, NKCC1, PPP1R141 |
|---|---|
| Chromosome | 5: 128083766-128189677 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters |
| Biological process | Ion transport, Potassium transport, Sodium transport, Symport, Transport |
Function
Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.