CSDE1 — Cold shock domain containing E1

CSDE1 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CSDE1's module in each cell type

Cell type	Module	Shares the module with
Fibroblasts	Rho-ROCK Contractility Cytoskeletal	ANXA6, ATP2B4, CBX6, DYNLT3, GNG12, ITM2C, PPP1CB, ROCK1 +1 more	View in SCUBA
Gamma-delta T cells	Hippo Pathway Signaling TCR Signaling	ADAR, ARL8B, BAZ2A, CASC3, CCDC85C, CCNK, CDC73, CDK12 +24 more
Goblet cells	Ion Transport Homeostasis Housekeeping	APP, ATP1A1, CAPRIN1, EEF2, MAT2B, SLC12A2, TMEM123, VPS35	View in SCUBA
Macrophages	Autophagy Vesicular Trafficking Vesicular traficking	ACTR2, AHCYL1, ALKBH5, BECN1, BICD2, CAP1, CAPRIN1, COLGALT1 +32 more	View in SCUBA
Mucosal-associated invariant T cell	mRNA Processing Translation RNA processing & translation	ACTN4, CDC42SE1, DDX5, EIF4G1, GDI1, HNRNPU, MSN, NCL +7 more
Pericytes	ER-Actin Cytoskeletal Cytoskeletal	A2M, GTF2I, IQGAP1, KTN1, MAP4K4, SEC62, SERINC1, WASF2	View in SCUBA

About the gene

Synonyms	D1S155E, UNR
Chromosome	1: 114716913-114758676
Predicted location	Intracellular
Essential gene	No
Protein class	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Molecular function	RNA-binding

Function

RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA- binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules. (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.