SCUBA

SNTB2 — Syntrophin beta 2

SNTB2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SNTB2's module in each cell type

Cell typeModuleShares the module with
EndothelialLipid Droplet Hypoxia
Stress
BNIP3, CEMIP2, CNN3, FCGRT, FGD6, PLIN2, TSPAN4View in SCUBA
Gamma-delta T cellsChromatin Repression
DNA/chromatin regulation
CAPN12, CFAP210, CNOT10, EPS8L2, FKBP5, H1-10, HAGHL, IL6ST +8 more

About the gene

SynonymsD16S2531E, EST25263, SNT2B2, SNT3, SNTL
Chromosome16: 69187147-69309052
Predicted locationIntracellular
Essential geneNo
Protein classPlasma proteins, Predicted intracellular proteins
Molecular functionActin-binding, Calmodulin-binding

Function

Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.