SURF1 — SURF1 cytochrome c oxidase assembly factor
SURF1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SURF1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitochondrial Housekeeping Mitochondrial & OxPhos | ARL2, BRAT1, C11orf58, CCDC115, CD3E, CHMP4A, CHURC1, DPM3 +13 more | |
| Macrophages | Mitochondrial Complex Assembly Mitochondrial & OxPhos | COX14, LAMTOR1, MRPL43, NDUFA8, NDUFC1, SMIM26, TADA3, VPS28 | View in SCUBA |
About the gene
| Synonyms | SHY1 |
|---|---|
| Chromosome | 9: 133351758-133356676 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
Function
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.