TBC1D8 — TBC1 domain family member 8
TBC1D8 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TBC1D8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | LAYN+ tissue Treg Immune regulation | BEX3, CADM1, CHRNA6, EPHX2, FLVCR2, GNG8, IKZF4, LAPTM4B +7 more | View in SCUBA |
| Lymphatic endothelial | ECM-driven Migration migration & adhesion | FMNL2, GLIS3, LAMC1, MAML2, PCSK6, RAPH1, SGIP1, ST3GAL6 +2 more | View in SCUBA |
| Macrophages | PI3K Lipid Signaling Innate immunity | AGPAT4, AREG, DHX34, DNMBP, EEPD1, HIP1, IP6K1, IRAK2 +23 more | View in SCUBA |
About the gene
| Synonyms | AD3, GRAMD8, HBLP1, VRP |
|---|---|
| Chromosome | 2: 101007228-101252866 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | GTPase activation |
Function
May act as a GTPase-activating protein for Rab family protein(s)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.