GLIS3 — GLIS family zinc finger 3
GLIS3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GLIS3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Cytokine Chemokine Secretion Inflammatory | CCL2, CSF3, CXCL1, CXCL3, CXCL8, G0S2, IL6, RIPK2 +1 more | View in SCUBA |
| Gamma-delta T cells | Effector Cytokine Secretion Inflammation | APBA2, ASPH, CCL3, CCL4, CMC1, CYRIA, DTHD1, DTNBP1 +25 more | |
| Lymphatic endothelial | ECM-driven Migration migration & adhesion | FMNL2, LAMC1, MAML2, PCSK6, RAPH1, SGIP1, ST3GAL6, STK32B +2 more | View in SCUBA |
About the gene
| Synonyms | MGC33662, ZNF515 |
|---|---|
| Chromosome | 9: 3824127-4348392 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
| Molecular function | Activator, DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Acts both as a repressor and an activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.