FMNL2 — Formin like 2
FMNL2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
FMNL2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Venous EC Identity Endothelial cell development | CA4, CABP1, CD36, FABP5, IGFBP6, ISLR, LNX1, MGLL +6 more | View in SCUBA |
| Lymphatic endothelial | ECM-driven Migration migration & adhesion | GLIS3, LAMC1, MAML2, PCSK6, RAPH1, SGIP1, ST3GAL6, STK32B +2 more | View in SCUBA |
| Macrophages | MITF Lysosomal Program Lysosomal & pahgocytosis | ABHD3, ANKRD44, ARSB, C2CD5, CERS6, CHST11, CNST, DCTN4 +25 more | View in SCUBA |
| Monocytes | Macrophage Differentiation Developmental | C7orf50, CABP4, FCGR3B, IL3RA, MS4A4A, MSR1, PPM1N, PPP1R17 +3 more | View in SCUBA |
About the gene
| Synonyms | FHOD2, KIAA1902 |
|---|---|
| Chromosome | 2: 152335174-152649826 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.