ZNF131 — Zinc finger protein 131
ZNF131 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZNF131's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | GIMAP survival Immune regulation | ABLIM1, AKT3, ANKRD13D, ARL4C, C16orf54, CA5B, COPA, CRBN +16 more | View in SCUBA |
| Innate lymphoid cells | Transcriptional Activation DNA regulation & transcription | AKIRIN1, CHORDC1, FAM133B, FAM53C, GOLGB1, GTF2B, IDI1, MORF4L2 +9 more | View in SCUBA |
| Macrophages | ER Stress Response Stress | ARHGEF12, ATXN7, BTBD7, CD2AP, CLIP2, DAPK1, DST, ERN1 +14 more | View in SCUBA |
About the gene
| Synonyms | pHZ-10, ZBTB35 |
|---|---|
| Chromosome | 5: 43065176-43192021 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding, Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Plays a role during development and organogenesis as well as in the function of the adult central nervous system (By similarity). May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.