Abundant Transcript Baseline
Gene co-expression module in Enterocytes
| Category | Housekeeping |
|---|---|
| Genes | 15 |
| Annotation certainty | 2 of 5 |
| Annotation consistency | 7 of 15 genes have a known function matching the annotation |
Why this annotation
This is a mix of highly expressed housekeeping genes (MYL6, CALM2, SRP14, SERF2, CSTB) and epithelial markers (KRT8, SMIM22, LGALS3). It also contains mitochondrial genes (ATP5IF1, MPC2, CHCHD2, NDUFA4, C15orf48, PRELID1, GHITM). It shows high uniform detection with no specific program, likely a library-size-driven abundant-transcript axis. It is related to the neighboring OXPHOS modules.
Genes
ATP5IF1, C15orf48, CALM2, CHCHD2, CSTB, GHITM, KRT8, LGALS3, MPC2, MYL6, NDUFA4, PRELID1, SERF2, SMIM22, SRP14
Most correlated modules
- Electron Transport Chain · correlation 0.92
- ATP Synthase OXPHOS · correlation 0.88
- Respiratory Chain OXPHOS · correlation 0.84
- Oxidative Phosphorylation · correlation 0.83
- Respiratory Chain Subunits · correlation 0.82
- Mitochondrial Chaperonin · correlation 0.81
- Translation Elongation · correlation 0.81
- High-abundance housekeeping · correlation 0.78
Module annotations were drafted by a large language model from the module's genes, then reviewed and approved by a domain expert. See sources & licences.