MPC2 — Mitochondrial pyruvate carrier 2
MPC2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MPC2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Abundant Transcript Baseline Housekeeping | ATP5IF1, C15orf48, CALM2, CHCHD2, CSTB, GHITM, KRT8, LGALS3 +6 more | View in SCUBA |
| Gamma-delta T cells | G1/S Entry Cell cycle | CDKN2A, CKS2, CMC2, H2AZ1, H2AZ2, HMGB2, IFI27L1, KPNA2 +15 more | |
| Goblet cells | Oxidative Phosphorylation Mitochondrial & OxPhos | ATP5MF, COX7A2, COX7B, COX8A, CYCS, MPC1, NDUFC1, NDUFC2 +3 more | View in SCUBA |
| Hematopoietic progenitor cells | Erythroid Heme Synthesis Erythropoietic | BLVRB, HBQ1, HES6, MPST, REXO2, SMIM10, TMEM14B, TMEM14C +2 more | |
| Innate lymphoid cells | Pyruvate Metabolism Metabolism | ABCB1, ADI1, ARID1B, ATF7IP2, CFAP298, EIF2AK2, HNRNPH3, MINDY2 +10 more | View in SCUBA |
| Mucosal-associated invariant T cell | Metabolic Homeostasis Housekeeping | ADIPOR1, BIRC3, COQ10B, CREBRF, EIF1AX, GNAI3, H2AC20, KLF11 +10 more |
About the gene
| Synonyms | BRP44, DKFZP564B167, SLC54A2 |
|---|---|
| Chromosome | 1: 167916675-167937072 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Transport |
Function
Mediates the uptake of pyruvate into mitochondria.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.