ARHGAP25 — Rho GTPase activating protein 25
ARHGAP25 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGAP25's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Activated B cell B cell maturation | ARID3A, CFLAR, DUSP4, ENTPD1, MYO1F, PIK3R5, PLXNC1, PREX1 +6 more | View in SCUBA |
| Gamma-delta T cells | Butyrophilin gd Activation TCR Signaling | ABI1, ADD3, ANXA6, ARHGAP1, ARHGAP30, ARHGEF2, BTN3A1, BTN3A3 +16 more | |
| Hematopoietic progenitor cells | HOX HSC Program Stemness | ADGRE2, AFF1, HOXA3, HOXA6, HOXA9, JAML, LPIN1, MOB1B +3 more | |
| Mucosal-associated invariant T cell | Chromatin Epigenetic Regulation DNA/chromatin regulation | ACAP2, APBB1IP, ATM, CD247, CHD9, CLCN3, DDX17, FLI1 +14 more | |
| Natural Killer cells | Cytoskeletal Remodeling Cytoskeleton & motility | ADD3, ARHGEF3, C1orf21, CAPN2, CYTH1, DGKZ, DIP2A, GBP5 +4 more | View in SCUBA |
About the gene
| Synonyms | KIAA0053 |
|---|---|
| Chromosome | 2: 68679601-68826833 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.