CCDC69 — Coiled-coil domain containing 69
CCDC69 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CCDC69's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Germinal Center Maturation B cell maturation | BCAS4, BCL7A, DCK, DTX1, ITGAE, LSM10, NEIL1, POU2AF1 +5 more | View in SCUBA |
| Endothelial | Endothelial Quiescence Identity Endothelial cell development | CLIC2, CLSTN3, CPD, EPB41L4A, FOXF1, FZD4, IGFBP7, KCNE4 +7 more | View in SCUBA |
| Innate lymphoid cells | Lymphocyte Apoptosis Regulation Immune regulation | ANP32B, ARMCX3, CHD2, DHRS7, ELF1, FXYD5, GLIPR1, LEPROTL1 +14 more | View in SCUBA |
| Monocytes | Pentose Phosphate Pathway Innate immunity | ACAP1, AP5B1, CCND3, CITED4, CORO2A, DYSF, EIF4E3, FLOT2 +4 more | View in SCUBA |
About the gene
| Synonyms | DKFZP434C171, FLJ13705 |
|---|---|
| Chromosome | 5: 151181052-151224093 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.