CPD — Carboxypeptidase D
CPD belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CPD's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR Complex Activation TCR/AP1/NFKb pathway | ABHD17A, ACTR3, C1GALT1, CD2, CD3D, CD3E, CD3G, CD81 +14 more | View in SCUBA |
| Endothelial | Endothelial Quiescence Identity Endothelial cell development | CCDC69, CLIC2, CLSTN3, EPB41L4A, FOXF1, FZD4, IGFBP7, KCNE4 +7 more | View in SCUBA |
| Gamma-delta T cells | ER Stress Response Stress | ATP1B3, ATP2A2, BACH1, EIF2AK3, FAM118A, G3BP2, GRK5, HBP1 +13 more | |
| Macrophages | Phagocytic Endolysosomal Lysosomal & pahgocytosis | ABHD2, ACTN4, AP3S1, ARF6, ATP6V1B2, CD151, CERS2, CNIH1 +27 more | View in SCUBA |
| Mucosal-associated invariant T cell | Hypoxia-ER Stress Stress | ANKHD1, ARID1A, ARID4B, ATXN7, CEMIP2, CTDP1, EIF2AK3, ELF1 +5 more | |
| Neutrophils | Myeloid Inflammatory Activation Inflammatory | AQP9, FPR1, ITGAX, LITAF, MXD1, NABP1, NAMPT, SDCBP +5 more |
About the gene
| Synonyms | GP180 |
|---|---|
| Chromosome | 17: 30378927-30469989 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Carboxypeptidase, Hydrolase, Metalloprotease, Protease |
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.