EVI2B — Ecotropic viral integration site 2B
EVI2B belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
EVI2B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell activation signaling B cell maturation | ANKRD44, BLK, BTN3A2, GAPT, GPSM3, LBH, LTB, LY86 +9 more | View in SCUBA |
| CD4⁺ T cells | Post-transcriptional regulation RNA processing | BCL11B, CCDC14, CHD2, CHD6, CREBZF, DDX39B, DNASE1, FAM78A +21 more | View in SCUBA |
| Hematopoietic progenitor cells | MHC-I Antigen Presentation Myeloid development | ACTB, B2M, CALM2, CAPG, CYBA, EVI2A, FUT7, HLA-A +10 more | |
| Innate lymphoid cells | NK Homing Circulating Homing & TEM | ADD3, ANXA1, APOBEC3G, C16orf54, C1orf162, CAPG, CASP4, CAST +37 more | View in SCUBA |
| Neutrophils | Neutrophil Chemotaxis Receptors Chemotaxis | CEBPD, CXCR1, CXCR2, FCGR3A, FCGR3B, NRBF2, WAS, YPEL3 |
About the gene
| Synonyms | CD361, D17S376, EVDB |
|---|---|
| Chromosome | 17: 31303770-31314105 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | CD markers, Predicted membrane proteins |
Function
Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.