MTSS1 — MTSS I-BAR domain containing 1
MTSS1 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MTSS1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell activation signaling B cell maturation | ANKRD44, BLK, BTN3A2, EVI2B, GAPT, GPSM3, LBH, LTB +9 more | View in SCUBA |
| Fibroblasts | ICC contractility Gut motility | BEX1, BTC, DES, HACD1, HSPB7, IL17B, KCNMA1, LDB3 +7 more | View in SCUBA |
| Gamma-delta T cells | Cytotoxic Effector Program cytotoxicity | ADGRG1, ANXA4, CADM1, CX3CR1, FCGR3A, FGFBP2, FGL2, GNLY +14 more | |
| Macrophages | Monocyte Lipid Metabolism Lipid metabolism | ATP13A3, CEP170, CHIC2, COQ10B, CSGALNACT2, ENOSF1, HIPK2, HMGXB3 +14 more | View in SCUBA |
| Monocytes | Immediate Early Activation Stress | ARRDC2, GALR2, IER5L, MRPL55, NDUFA12, NXT1, RRAS, SLC7A7 +3 more | View in SCUBA |
| Natural Killer cells | Cytotoxic NK Maturation Cytotoxicity | ADGRG1, AKR1C3, CXCR2, FCGR3A, FGFBP2, GK5, LGR6, PRF1 +4 more | View in SCUBA |
About the gene
| Synonyms | KIAA0429, MIM, MIMA, MIMB |
|---|---|
| Chromosome | 8: 124550784-124728473 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Actin-binding |
Function
May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.