GPNMB — Glycoprotein nmb
GPNMB belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GPNMB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Submucosal Fibroblast Developmental | ADAMTS19, ANGPTL7, C7, CHRDL1, DPT, GDF6, HAND2, JAM2 +9 more | View in SCUBA |
| Macrophages | ER-Lysosome Trafficking Vesicular traficking | BPNT2, CALU, CLPTM1L, CTSB, DHRS7, EMC10, GBA1, GNS +21 more | View in SCUBA |
| Monocytes | Tissue-Resident Macrophage Tissue adaptation | DAB2, ETV5, FOLR2, FRMD4A, ITGB5, LGMN, LILRB5, LYVE1 +7 more | View in SCUBA |
| Smooth muscle cells | Pericyte Notch Identity Development | CD59, EIF1, HEYL, IFITM2, IGFBP7, INAFM1, ITM2B, PDGFRB +2 more | View in SCUBA |
About the gene
| Synonyms | HGFIN, NMB |
|---|---|
| Chromosome | 7: 23235967-23275108 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
Function
Could be a melanogenic enzyme
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.