LYZ — Lysozyme
LYZ belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
LYZ's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Crypt antimicrobial progenitor Antibacterial | CAMK1D, CHRM3, DIAPH2, EMP2, HES1, IFITM2, PTPN13, SULF2 | View in SCUBA |
| Goblet cells | Inflammatory Goblet Remodeling Stress | C2CD4A, CLCA1, COL16A1, FMOD, GALNT8, GPX2, IFITM2, KCNE3 +3 more | View in SCUBA |
| Monocytes | Classical Monocyte Activation Inflammatory | CAPG, LGALS1, MCEMP1, PDLIM7, S100A8, S100A9, SERPINB1, TALDO1 +1 more | View in SCUBA |
About the gene
| Chromosome | 12: 69348381-69354234 |
|---|---|
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins |
| Molecular function | Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase |
Function
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.