SGCB — Sarcoglycan beta
SGCB belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SGCB's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Inflammatory Lipid Metabolism Metabolite transfer | ACSL4, APOL1, CDK2AP2, COPS8, GBE1, GOLM1, MAPRE1, NPC1 +5 more | View in SCUBA |
| Fibroblasts | Actin Cytoskeletal Organization Cytoskeletal | ACP1, AKR7A2, ARL3, CAPZB, DERL1, GDE1, LEPROTL1, LIMS1 +8 more | View in SCUBA |
About the gene
| Synonyms | A3b, LGMD2E, SGC |
|---|---|
| Chromosome | 4: 52020706-52038299 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
Function
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.