SNN — Stannin
SNN belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SNN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Activation/Migration BCR/AP1/NFKb pathway | AHNAK, DUSP10, DUSP8, GGA1, GPR183, GPR65, IDS, KLF6 +11 more | View in SCUBA |
| CD4⁺ T cells | T cell Coinhibition Immune regulation | BTLA, CASD1, CFAP36, DUSP14, FCHSD2, HIVEP2, IFNGR2, KLF7 +7 more | View in SCUBA |
| Gamma-delta T cells | ER Stress Response Stress | ATP1B3, ATP2A2, BACH1, CPD, EIF2AK3, FAM118A, G3BP2, GRK5 +13 more | |
| Macrophages | JAK-STAT Cytokine Response Inflammatory | BCL2A1, CCRL2, CDC42EP2, DCUN1D3, IRF1, NFKBIE, PHLDA2, SOCS3 | View in SCUBA |
| Monocytes | Inflammatory Cell Death Inflammatory | ARL4C, BTG3, CD63, HIC1, MFSD2A, NINJ1, PID1, TRIP10 | View in SCUBA |
About the gene
| Chromosome | 16: 11668455-11679152 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Plays a role in the toxic effects of organotins. Plays a role in endosomal maturation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.