TROAP — Trophinin associated protein
TROAP belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TROAP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Mitotic Kinase Cascade Cell cycle | AURKA, CCNB1, CCNB2, CDC20, CDC25B, DEPDC1, FAM72C, FAM72D +6 more | View in SCUBA |
| Goblet cells | G2/M Cyclin Program Cell cycle | ARL6IP1, CCNB1, CCNB2, CDC20, CENPE, CENPF, CEP55, DLGAP5 +5 more | View in SCUBA |
| Hematopoietic progenitor cells | Mitotic Spindle Cell cycle | BIRC5, CCNB2, CDC20, CDKN3, CEP55, DLGAP5, HMMR, MKI67 +1 more | |
| Monocytes | Mitotic Cell Cycle Cell cycle | BIRC5, CENPF, H1-5, H2AC14, MKI67, PCLAF, PTTG1, STMN1 | View in SCUBA |
About the gene
| Synonyms | TASTIN |
|---|---|
| Chromosome | 12: 49323236-49331731 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Predicted intracellular proteins |
| Biological process | Cell adhesion |
Function
Could be involved with bystin and trophinin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.