TUBB6 — Tubulin beta 6 class V
TUBB6 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TUBB6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Nuclear Transport Housekeeping | ALYREF, BANF1, CNIH4, COX8A, HAUS1, HMGN1, ILF2, LSM5 +8 more | View in SCUBA |
| Fibroblasts | Actin Cytoskeleton Cytoskeletal | ACTB, CAPZA2, CFL1, CMTM6, COX8A, KIF5B, MORF4L2, NDUFS5 +6 more | View in SCUBA |
| Monocytes | Integrin-mediated Migration Migration & adhesion | DNAAF1, EIF4E, ITGA5, ITGB8, LMNA, MSC, NRIP3, PHLDA1 +7 more | View in SCUBA |
| Smooth muscle cells | Microtubule biogenesis Cytoskeletal | ACOT7, FBXL22, ILF2, LIMS2, NUCB2, PGRMC1, PHGDH, PPP2R1A +3 more | View in SCUBA |
About the gene
| Synonyms | HsT1601, MGC4083 |
|---|---|
| Chromosome | 18: 12307669-12344320 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.