UGP2 — UDP-glucose pyrophosphorylase 2
UGP2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
UGP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | IL10/cytokine signaling Immune regulation | CASK, CCDC141, FOXN3, IL10RA, IL7, SLC12A6, STAMBPL1, TMEM154 +4 more | View in SCUBA |
| Innate lymphoid cells | RNA Processing & Proteostasis RNA processing & translation | ATP5PD, CIRBP, COPS6, DPY30, MORF4L1, MYDGF, PDIA6, PNISR +5 more | View in SCUBA |
| Mucosal-associated invariant T cell | Integrin Actin Adhesion migration & adhesion | ACTR2, ANKRD10, ATP2B1, DDX46, HP1BP3, HPS3, JAK1, LINS1 +11 more | |
| Natural Killer cells | Mature NK Identity Differentiation | ABCB1, ADAM28, ADGRG3, CCDC141, CD160, CMTM7, DZIP3, IKZF3 +5 more | View in SCUBA |
About the gene
| Synonyms | SVUGP2, UGP1, UGPP1 |
|---|---|
| Chromosome | 2: 63840952-63891562 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Nucleotidyltransferase, Transferase |
Function
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.