XPO6 — Exportin 6
XPO6 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
XPO6's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TCR Inhibitory Signaling Exhaustion | AFF4, CBLB, CCNH, CCNT1, CHD2, CRYBG1, FYN, ISG20 +9 more | |
| Macrophages | Myeloid Receptor Signaling Innate immunity | ADGRE5, ANKFY1, ANKIB1, ATP1B1, CPT1A, DNAJC13, DOCK7, EPS15 +29 more | View in SCUBA |
| Mucosal-associated invariant T cell | Hypoxia-ER Stress Stress | ANKHD1, ARID1A, ARID4B, ATXN7, CEMIP2, CPD, CTDP1, EIF2AK3 +5 more | |
| Neutrophils | PI3K Migration Signaling Migration & adhesion | CPPED1, CREB5, CYTIP, PELI1, PTEN, RASSF3, SEMA4D, SH2D3C +3 more |
About the gene
| Synonyms | FLJ22519, KIAA0370, RANBP20 |
|---|---|
| Chromosome | 16: 28097976-28211965 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Metabolic proteins, Predicted intracellular proteins |
| Biological process | Protein transport, Transport |
Function
Mediates the nuclear export of actin and profilin-actin complexes in somatic cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.