BBX — BBX high mobility group box domain containing
BBX belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BBX's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Chromatin Regulation DNA/chromatin regulation | AKAP9, ANKRD12, CHD2, CHD7, IRF1, KDM7A, L3MBTL3, MAP3K1 +8 more | View in SCUBA |
| Macrophages | TGF-beta Signaling Inflammatory | APPL1, C6orf89, CCDC50, CREB3L2, HCLS1, NCKAP1L, NFIC, POGK +9 more | View in SCUBA |
| Smooth muscle cells | Vasoconstrictor Signaling Contractility | ARHGAP29, ATP10A, CDK18, CSRP2, EDNRA, GPAT2, NR3C1, NUDT4 +4 more | View in SCUBA |
About the gene
| Synonyms | HBP2, HSPC339, MDS001 |
|---|---|
| Chromosome | 3: 107522936-107811339 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Transcription factors |
| Molecular function | DNA-binding |
| Biological process | Transcription, Transcription regulation |
Function
Transcription factor that is necessary for cell cycle progression from G1 to S phase
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.