PPFIBP1 — PPFIA binding protein 1
PPFIBP1 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPFIBP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | ILC Survival Residency Gut residency | ARID4B, BAZ1A, BCL2A1, CD44, CSF2, CTSH, CXCL8, DUSP4 +25 more | View in SCUBA |
| Lymphatic endothelial | Actin Cytoskeletal Scaffold Cytoskeletal | CCDC102B, CCND3, DAAM1, DPYSL3, EPB41L2, GOLM2, GPATCH2, KLHL4 +1 more | View in SCUBA |
| Pericytes | Pericyte Vascular Identity Developmental | AHR, ARHGAP29, CA4, CD46, MEF2C, MYO6, NOTCH1, PDE1C +10 more | View in SCUBA |
| Smooth muscle cells | Cytoskeletal Scaffolding Cytoskeletal | AKAP6, C3orf70, CNST, CTTNBP2, DACT3, IQGAP1, KIF13A, KLHL23 +8 more | View in SCUBA |
About the gene
| Synonyms | hSGT2, hSgt2p, L2, SGT2 |
|---|---|
| Chromosome | 12: 27523431-27695564 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Plasma proteins, Predicted intracellular proteins |
Function
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.