GYG1 — Glycogenin 1
GYG1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GYG1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cell motility/adhesion migration & adhesion | ANXA2, CCDC107, CYBA, FAM50A, GLIPR2, GRAP2, ITM2B, LCP1 +14 more | View in SCUBA |
| Innate lymphoid cells | Actin Cytoskeletal Regulation Cytoskeleton & motility | AQP3, CCDC57, CLPTM1, COTL1, DCAF11, GSN, MZT2B, NAA38 +7 more | View in SCUBA |
| Macrophages | Glycogen Metabolism Housekeeping | ARL2BP, BTF3L4, CAPN1, CD47, CRLS1, DCTD, DSTN, GLOD4 +24 more | View in SCUBA |
| Mucosal-associated invariant T cell | ER Stress Response Protein processing & ER | ACADVL, APOL3, HLA-F, HSP90B1, LENG8, MAP4K1, PIM1, PLEKHF1 +4 more | |
| Neutrophils | Pentose Phosphate Pathway Housekeeping | ANXA3, ARPC2, CAP1, CDA, HMGB2, LBR, PGD, SNX3 +1 more |
About the gene
| Synonyms | GYG |
|---|---|
| Chromosome | 3: 148991408-149031775 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Glycogen biosynthesis |
Function
Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to internal tyrosine residues and these chains act as primers for the elongation reaction catalyzed by glycogen synthase.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.