MZT2B — Mitotic spindle organizing protein 2B
MZT2B belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MZT2B's module in each cell type
About the gene
| Synonyms | FAM128B, FLJ14346, MOZART2B |
|---|---|
| Chromosome | 2: 130181737-130190729 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Required for the recruitment and the assembly of the gamma- tubulin ring complex (gTuRC) at the centrosome. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.