SNX20 — Sorting nexin 20
SNX20 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SNX20's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | ILC1 Lymphocyte Signaling Immune regulation | CDIPT, CNPY3, DBNL, ENG, IL16, LIMD2, LSM2, MAPKAPK3 +11 more | View in SCUBA |
| Macrophages | Inflammasome Pyroptosis Inflammatory | ARRDC1, ATOX1, CSTA, EMP2, ENPP2, FBXO6, GSDMD, HLA-DQB2 +12 more | View in SCUBA |
| Mucosal-associated invariant T cell | Chemokine Receptor Migration migration & adhesion | CCR1, CCR2, CCR5, CD47, FAM78A, KRIT1, LUC7L3, MTG1 +6 more |
About the gene
| Synonyms | SLIC-1, SLIC1 |
|---|---|
| Chromosome | 16: 50666300-50681353 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Protein transport, Transport |
Function
May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.