STX3 — Syntaxin 3
STX3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
STX3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Lymphatic endothelial | DNA Damage Apoptosis DNA/chromatin regulation | AZIN1, BAZ1A, HNRNPC, IVNS1ABP, MAPK6, OTUD4, PHLDB2, SPEN +4 more | View in SCUBA |
| Macrophages | NF-κB AP-1 Signaling Inflammatory | ABL2, AGAP3, ARL8B, ATP1B3, ATP6V1H, B4GALT1, C5AR2, CDKN1A +21 more | View in SCUBA |
About the gene
| Synonyms | STX3A |
|---|---|
| Chromosome | 11: 59713456-59805882 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Biological process | Neurotransmitter transport, Transport |
Function
Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles. Essential for survival of retinal photoreceetors. Functions as a regulator of gene expression
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.