THSD7A — Thrombospondin type 1 domain containing 7A
THSD7A belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
THSD7A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | EC Barrier Integrity Endothelial cell development | ABCB1, ADCY4, AQP3, ARHGAP31, CRYBG3, EPS8, FGR, FRYL +14 more | View in SCUBA |
| Lymphatic endothelial | Lymphatic EC Identity Gut residence | CD36, CERS6, CHST15, DOCK5, EPS15, FRMD4B, FRY, IL7 +4 more | View in SCUBA |
| Pericytes | Vascular Identity TFs Developmental | CCDC85A, EXOC6, GIPC2, HHEX, MCTP1, SLC16A14, SOX7, TSPAN7 | View in SCUBA |
About the gene
| Synonyms | KIAA0960 |
|---|---|
| Chromosome | 7: 11370365-11832198 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Predicted membrane proteins, Predicted secreted proteins |
| Biological process | Angiogenesis, Differentiation |
Function
Plays a role in actin cytoskeleton rearrangement. The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.