ZNF703 — Zinc finger protein 703
ZNF703 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ZNF703's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Hypoxia/metabolic stress Stress | ALG13, ARL4A, C9orf72, HIP1R, PDE4B, SC5D, SLC2A3, TENT5C +2 more | View in SCUBA |
| Monocytes | Non-classical Monocyte Innate immunity | CD79B, CDH23, CDKN1C, CHST7, CKB, CYFIP2, KNDC1, LYPD2 +6 more | View in SCUBA |
| Smooth muscle cells | Glucocorticoid Metallothionein Response Stress | CEBPB, CEBPD, FKBP5, MT1E, MT1M, MT1X, MT2A, PNRC1 +3 more | View in SCUBA |
About the gene
| Synonyms | FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1 |
|---|---|
| Chromosome | 8: 37695782-37700019 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Predicted intracellular proteins |
| Molecular function | Repressor |
| Biological process | Transcription, Transcription regulation |
Function
Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.