MT1X — Metallothionein 1X
MT1X belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MT1X's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Immunoproteasome IFN Anti-viral | APRT, BATF, MT2A, NIT2, PSMB9, PSME1, PSME2, VAMP5 | View in SCUBA |
| Enterocytes | Metallothionein metal response Stress | BLVRB, MT1E, MT1F, MT1G, MT1H, MT1M, MT2A, TMEM176A +1 more | View in SCUBA |
| Fibroblasts | Chemokine-secreting Fibroblasts Inflammatory | CA12, CCBE1, CHI3L2, CPXM2, CXCL13, CXCL5, GAS1, GPM6B +10 more | View in SCUBA |
| Smooth muscle cells | Glucocorticoid Metallothionein Response Stress | CEBPB, CEBPD, FKBP5, MT1E, MT1M, MT2A, PNRC1, TSC22D1 +3 more | View in SCUBA |
About the gene
| Synonyms | MT-1l, MT1 |
|---|---|
| Chromosome | 16: 56682470-56684196 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.