BLCAP — BLCAP apoptosis inducing factor
BLCAP belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BLCAP's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Actomyosin Contractility Cytoskeletal | BCL7C, C20orf204, CMBL, CTDSPL, DDB2, FLRT2, ITM2C, KLHL4 +11 more | View in SCUBA |
| Lymphatic endothelial | Vascular Lumen Formation endothelial development | ANXA4, CD47, GINM1, LMAN1, MTDH, RASIP1, STAT1 | View in SCUBA |
About the gene
| Synonyms | BC10 |
|---|---|
| Chromosome | 20: 37492472-37527931 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Apoptosis, Cell cycle |
Function
Acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa- B-independent mechanisms. Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.