CKAP4 — Cytoskeleton associated protein 4
CKAP4 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CKAP4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Nuclear Transport Housekeeping | AAMDC, ANP32B, CBX5, CDK4, COMMD4, COQ2, CSE1L, DAZAP1 +18 more | View in SCUBA |
| Goblet cells | Mucin O-Glycosylation Mucus production & secretion | ACLY, ASPH, C9orf152, ESRP1, FABP2, IL13RA1, PLPP5, RAB2A +8 more | View in SCUBA |
| Monocytes | Classical Monocyte Trafficking Migration & adhesion | ANXA6, EMB, F5, GCA, MAP2K6, MPP7, MSRB1, PADI4 +4 more | View in SCUBA |
| Neutrophils | Specific Granule Release Degranulation | BMX, CA4, CLEC4D, GPAT3, KBTBD7, MMP9, VIM | |
| Smooth muscle cells | Growth Arrest Stress Stress | BOK, C14orf132, CNKSR3, MXRA7, NBPF1, PTGS1, WEE1 | View in SCUBA |
About the gene
| Synonyms | CLIMP-63, ERGIC-63, P63 |
|---|---|
| Chromosome | 12: 106237881-106304279 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
Function
Mediates the anchoring of the endoplasmic reticulum to microtubules. High-affinity epithelial cell surface receptor for the FZD8- related low molecular weight sialoglycopeptide APF/antiproliferative factor. Mediates the APF antiproliferative signaling within cells
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.