CSF2 — Colony stimulating factor 2
CSF2 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CSF2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Cytotoxic effector Cytotoxicity | ADGRG1, ATP8B4, CCL3, CCL4, CCL4L2, FASLG, GNLY, GZMB +10 more | View in SCUBA |
| Innate lymphoid cells | ILC Survival Residency Gut residency | ARID4B, BAZ1A, BCL2A1, CD44, CTSH, CXCL8, DUSP4, ENTPD1 +25 more | View in SCUBA |
| Lymphatic endothelial | Genotoxic Innate Inflammation Inflammation | CSF3, E2F7, GBP2, NBN, PLA1A, RIPK2, SELENOM, SQOR +1 more | View in SCUBA |
| Natural Killer cells | EGR2/3 NK Activation activation | AMD1, CHD4, CRTAM, DNAJB9, EGR2, EGR3, GADD45A, MAP2K3 +4 more | View in SCUBA |
About the gene
| Synonyms | GM-CSF, GMCSF |
|---|---|
| Chromosome | 5: 132073789-132076170 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, Predicted secreted proteins |
| Molecular function | Cytokine, Growth factor |
Function
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.