CTBP2 — C-terminal binding protein 2
CTBP2 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CTBP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Tissue-resident gd T Tissue residence | AKR1C3, ASCL2, BFSP1, CARNS1, CD320, CES1, CMKLR1, CXCR1 +21 more | |
| Macrophages | Endosomal Vesicle Trafficking Vesicular traficking | ADAM17, AP3B1, ARFGEF1, ARID1B, ARK2N, ASAP1, ATF6, ATP11A +48 more | View in SCUBA |
| Smooth muscle cells | KLF6/ZNF24 regulators Activation | ACSL3, ARHGAP1, KLF6, PLEKHA4, SCAF11, TNFAIP8L3, ZNF24 | View in SCUBA |
About the gene
| Synonyms | ribeye |
|---|---|
| Chromosome | 10: 124984317-125161170 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Oxidoreductase, Repressor |
| Biological process | Differentiation, Host-virus interaction, Transcription, Transcription regulation |
Function
Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). Isoform 2 probably acts as a scaffold for specialized synapses
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.