PLEKHA4 — Pleckstrin homology domain containing A4
PLEKHA4 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PLEKHA4's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Actomyosin Contractility Cytoskeletal | BCL7C, BLCAP, C20orf204, CMBL, CTDSPL, DDB2, FLRT2, ITM2C +11 more | View in SCUBA |
| Glial cells | Hyaluronan-CD44 Remodeling ECM remodeling | C4orf48, CBX3, CD44, HAS2, HES4, MIA, WWTR1 | View in SCUBA |
| Smooth muscle cells | KLF6/ZNF24 regulators Activation | ACSL3, ARHGAP1, CTBP2, KLF6, SCAF11, TNFAIP8L3, ZNF24 | View in SCUBA |
About the gene
| Synonyms | PEPP1 |
|---|---|
| Chromosome | 19: 48837092-48868617 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.