ERGIC3 — ERGIC and golgi 3
ERGIC3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ERGIC3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Translation Initiation RNA processing & translation | BTF3, C12orf57, COMMD6, COX4I1, COX7C, EEF1B2, EEF1D, EEF1G +18 more | |
| Innate lymphoid cells | Cellular Metabolic Maintenance Metabolism | ADIPOR1, APH1A, ARF5, BCAP31, CLIC1, CSNK2B, CYB5R3, DHPS +13 more | View in SCUBA |
| Macrophages | ER Protein Quality Control Lysosomal & pahgocytosis | ACP2, C5orf15, CLN5, CS, CTBP1, FUT11, GANAB, GLB1 +18 more | View in SCUBA |
| Smooth muscle cells | Sparse Mitoribosomal Housekeeping Housekeeping | CEP63, CIB1, CTNNA1, FBXO17, LEPROT, MRPL32, MRPL41, MRPS7 +6 more | View in SCUBA |
About the gene
| Synonyms | C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84 |
|---|---|
| Chromosome | 20: 35542038-35557634 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | ER-Golgi transport, Transport |
Function
Possible role in transport between endoplasmic reticulum and Golgi. Positively regulates trafficking of the secretory proteins SERPINA1/alpha1-antitrypsin and HP/haptoglobin
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.