GLA — Galactosidase alpha
GLA belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GLA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | ATF4 Stress Response Stress | ATF4, BRD2, CCNYL1, ERO1B, FUS, HMGCS1, INSIG1, KLF10 +3 more | View in SCUBA |
| Macrophages | RAS-MAPK Signaling Housekeeping | ARF4, ATG12, CAMTA1, CDC37, CHMP4B, ETFA, HMGA1, JAK1 +26 more | View in SCUBA |
| Monocytes | NR4A Immediate-Early Inflammatory | ANKRD37, CHMP1B, CKS2, CYCS, EIF4A3, ETV3, NR4A1, NR4A2 +4 more | View in SCUBA |
| Mucosal-associated invariant T cell | TCR-Induced Early Response TCR Signaling | ATF3, EGR1, HMGCS1, IER3, NR4A1, NUP58, PPP1R15B, RHOB +3 more |
About the gene
| Synonyms | GALA |
|---|---|
| Chromosome | X: 101393273-101408012 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Glycosidase, Hydrolase |
| Biological process | Lipid metabolism |
Function
Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.