NUP58 — Nucleoporin 58
NUP58 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NUP58's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Pre-mRNA Splicing RNA processing & translation | BCLAF1, CENPC, CLK1, CNOT1, COG3, COPS2, DDX24, DDX3X +11 more | |
| Macrophages | ER-Golgi Trafficking Vesicular traficking | ADD1, AFTPH, AZIN1, COPA, DYNC1H1, HNRNPC, JOSD1, LCP2 +23 more | View in SCUBA |
| Mucosal-associated invariant T cell | TCR-Induced Early Response TCR Signaling | ATF3, EGR1, GLA, HMGCS1, IER3, NR4A1, PPP1R15B, RHOB +3 more |
About the gene
| Synonyms | KIAA0410, NUP45, NUPL1 |
|---|---|
| Chromosome | 13: 25301524-25365390 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters |
| Biological process | mRNA transport, Protein transport, Translocation, Transport |
Function
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.