RCAN3 — RCAN family member 3
RCAN3 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RCAN3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling TCR/AP1/NFKb pathway | AP3M2, ATP1B3, CREM, CRYBG1, DCTN6, EZR, FAM177A1, FTH1 +19 more | View in SCUBA |
| Gamma-delta T cells | TCR Signal Regulation TCR Signaling | ADORA2A, ANO9, CAMK4, CASK, CCR5, CD84, CDC14A, CXCR6 +22 more | |
| Natural Killer cells | NK Tissue Residency Gut residency | ENTPD1, GEM, GPR171, ITGA1, KLHL23, LDLRAD4, PHYKPL | View in SCUBA |
About the gene
| Synonyms | DSCR1L2 |
|---|---|
| Chromosome | 1: 24502351-24541040 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.