ANTKMT — Adenine nucleotide translocase lysine methyltransferase
ANTKMT belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANTKMT's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Metabolic Housekeeping Housekeeping | ACAP1, ATP6V0E2, B3GAT3, CCDC57, CHN2, CMTM3, DCTD, DGUOK +12 more | |
| Macrophages | Complex I / NADH Dehydrogenase Mitochondrial & OxPhos | AHCY, ANP32A, APEX1, ARL2, ATIC, ATP5F1A, ATP5ME, CCDC85B +31 more | View in SCUBA |
| Mucosal-associated invariant T cell | Mature Effector MAIT T cell maturation | ADD3, APOBEC3G, CCL5, CXXC5, FHL3, GZMK, ITGA6, ITGB2 +7 more |
About the gene
| Synonyms | C16orf24, FAM173A, MGC2494 |
|---|---|
| Chromosome | 16: 720581-722590 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Methyltransferase, Transferase |
Function
Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration. Probably also trimethylates ANT1/SLC25A4
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.