GIMAP8 — GTPase, IMAP family member 8
GIMAP8 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GIMAP8's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | GIMAP survival Immune regulation | ABLIM1, AKT3, ANKRD13D, ARL4C, C16orf54, CA5B, COPA, CRBN +16 more | View in SCUBA |
| Endothelial | Arterial EC Homeostasis Endothelial cell development | APOL3, BMX, EXOC6, FAXDC2, FTH1, GABARAPL1, GAS6, GIMAP1 +10 more | View in SCUBA |
| Gamma-delta T cells | T cell Survival T cell maturation | ARFRP1, BCL2L1, C6orf47, CHD9, DAXX, DEF6, DENND2D, DHPS +26 more | |
| Lymphatic endothelial | Glycolytic Housekeeping Housekeeping | CALCOCO2, CANX, CAP1, DPYSL2, DYNC1I2, EIF2S2, ENO1, PGAM1 +1 more | View in SCUBA |
| Macrophages | Myeloid Signaling Regulation Innate immunity | ADGRG6, AOAH, CCDC170, CD302, CMKLR1, CPED1, DIPK2A, FAM13A +38 more | View in SCUBA |
| Monocytes | GIMAP activation Housekeeping | FGD2, GIMAP1, GIMAP4, GIMAP6, GIMAP7, IRF2, NAGK, P2RY13 +2 more | View in SCUBA |
| Mucosal-associated invariant T cell | Lymphocyte Survival T cell maturation | ARHGEF3, BTN3A1, CNTRL, ME2, PCMTD1, PRKACB, RSBN1L, SHPRH +4 more |
About the gene
| Synonyms | DKFZp667I133, hIAN6, IAN9 |
|---|---|
| Chromosome | 7: 150450630-150479393 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.