DUOXA2 — Dual oxidase maturation factor 2
DUOXA2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DUOXA2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | DUOX2 oxidative defense Antibacterial | CD55, CEACAM5, DUOX2, ENSG00000267881, HK2, ITGA2, TPM4 | View in SCUBA |
| Goblet cells | DUOX2 Epithelial Inflammation Stress | AKAP13, BIRC3, DUOX2, DUSP4, IL2RG, IL32, ISG15, RNF213 +1 more | View in SCUBA |
About the gene
| Chromosome | 15: 45114326-45118421 |
|---|---|
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted membrane proteins |
| Biological process | Protein transport, Transport |
Function
Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2. May play a role in thyroid hormone synthesis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.